Resistance training load does not determine hypertrophy

(physoc.onlinelibrary.wiley.com)

165 points | by Luc 15 hours ago ago

177 comments

  • formichunter 3 minutes ago ago

    Why is this article showing up on New Year's Day like the flock of newbie gym customers attracted to the gym only to quit 30 days from now? Every year without fail.

    Let's ignore this article for a moment.

    Overall factors that REALLY matter building muscle: 1. Consistency - Working out each muscle group at least once a week....every week. 2. Diet - Making sure you are consuming enough protein in your diet, approximately 1gram/pound of body weight...or near it or even best you can. Total calories consumed a day should match any online calculator for your age and activity level. 3. Sleep! 4. Sleep! 5. Vary your workout - some weeks high reps low weight and some weeks low reps high weight. Why? Never let your body know what you're doing and shock it as best you can. Always try to exert yourself enough to be sore within 48 hours of a workout.

    Now multiply this over a few years.

    Stop reading these studies thinking there is some optimal way! It's just hard work over time.

    BTW: In winter I bench press 350 pounds or 159KG. I run 10KM or 6.1 miles twice a week and increase it a little bit in summer. I pull my body in two different directions because I love both.

  • AstroBen 12 hours ago ago

    > Healthy, recreationally active but untrained young males

    Yeah this is why. Anything you do as an untrained person is going to get you newbie gains. It's just really easy to improve initially. Doesn't mean it'll work after the first 6 months

    • timr 8 hours ago ago

      Perhaps there's some unmeasured influence, but this study was looking only at the difference between growth within subjects vs between subjects. If the subjects were all "newbies", then that doesn't explain the results.

      They're essentially saying that individual genetics explain the majority of the variation seen as a response to muscle stimulus in their test subjects, not the mass used, because the variation within the test cohorts was greater than the variation between them. You can argue that, if they didn't test experienced lifters the results might be different in that population, but you can't dismiss the results on those grounds.

      • raducu 6 hours ago ago

        > not the mass used.

        Completely anecdotal, but when I was 18, in highschool, I trained in the gym in my hometown, supervised with a trainer, 12 reps per muscle group, very modest gains.

        I move to university, start reading a fitness forum where people were saying do max 6 reps if you want big gains.

        I also started supplementing with whey protein, and within 3 months the gains were spectacular, everybody noticed, I felt on fire, best time of my life, I miss so much how great I felt in my own body.

        I've seen other colleagues and how they trained -- I can say there was 100% correlation that those people who were not training hard also did not have big gains. People who had enough breath left in them to chat in the gym simply did not gain as much as people I saw as training hard.

        Also for me, the 6 reps to exhaustion felt completely different then 12 reps (again, to complete exhaustion) -- immediately after the training it felt amazing to be alive, the world became a comfortable place, my anxiety completely vanished, and in the night and morning after an intense training (especially the legs and back) the erections and libido boost were out of this world, something I never felt with the 12 reps regimen.

        • vidarh 3 hours ago ago

          What do you consider gains? Consider that this paper looked specifically at hypertrophy (size), not strength. While they correlate, training for one or the other can be very different..

          "Traditionally" the rep ranges recommended for hypertrophy has typically been significantly higher than the ranges recommended for strength, but the number of sets recommended is often also significantly higher, often translating to significantly higher total volume.

          > I've seen other colleagues and how they trained -- I can say there was 100% correlation that those people who were not training hard also did not have big gains. People who had enough breath left in them to chat in the gym simply did not gain as much as people I saw as training hard.

          Well, yes, but training with lower weights and higher rep ranges does not automatically translate to "not training hard".

          Having gone through a period of really high rep training, including for a short period doing 1000 squats per day as an experiment, mostly bodyweight, that was far harder exercise than when I 1RM'd 200kg. But the effects are different.

          I much prefer Stronglifts and Madcow but because I favour strength over size, and it's far more time efficient, not because you can't also get results with more, lower-weight reps.

          • matwood 2 hours ago ago

            > Consider that this paper looked specifically at hypertrophy (size), not strength.

            I'm not sure where this idea came from that people do one or the other. Except for the advanced lifter, both will happen from either program. Show me a person who is really big and they are likely pretty strong as well (see Ronnie Coleman). Same with the other direction.

        • bendtb 6 hours ago ago

          Anecdotally as someone who strength trained on a recreational basis the last 20 years (and run a marathon just to see if I could), nothing beats heavy lifting.

          A Strong lifts 5x5 program build around squat, deadlifts, bench and shoulder press can always make me feel pumped for the day!

          • matwood 4 hours ago ago

            Same. Finding heavy lifting changed my life if I’m honest. The strength gains, body comp, and how I felt was amazing.

        • matwood 2 hours ago ago

          > People who had enough breath left in them to chat in the gym simply did not gain as much as people I saw as training hard.

          IDK. When I powerlifted the goal was to move the weight. I've almost passed out from heavy deadlifts, but was rarely out of breath. I also almost never chat in the gym because it's my meditative place, not because I couldn't chat :)

          • hunter-gatherer an hour ago ago

            I think what OP is specifically refering to is the intensity level that varies among individuals. I suspect that oft times when people train with a low weight/high rep scheme, they accidenrly let their intensity levels slip. I suspect that for most people, especially newer lifters, doing a high weight/low rep scheme makes keeping the workout for intense because it is easier to focus on being intense for a short time. Just a thought....

      • sedivy94 7 hours ago ago

        The activation energy or stimulus required for hypertrophy in untrained individuals is so low that it’s hard to differentiate the results. Studies like this absolutely need to be done in trained individuals if you want reliable data.

        • bluGill 4 hours ago ago

          Most people are untrained so this is useful reliable data for most people. However for those who actually care about results: they are trained, or soon will be andthis data doesn't apply.

    • andreareina 3 hours ago ago

      Brad Schoenfeld felt the same way, so he did the study on trained participants, and made the same finding: https://journals.lww.com/nsca-jscr/fulltext/2015/10000/Effec...

    • foldingmoney 10 hours ago ago

      exactly. when you're new, virtually any type of lifting you do is going to create sufficient stimulus to trigger maximum muscle growth, because you're going from 0 to 1. unfortunately, since the only people that researchers can usually convince to participate in their studies are untrained, this has led to an enormous amount of junk studies where they try to extrapolate the results to people who are not untrained.

    • matwood 4 hours ago ago

      Yeah. When was powerlifting seriously I spent months with my deadlift stuck on 525 pounds. I would measure progress by how many times I could just get the weight off the floor, then how far off the floor, etc… The newbie gains were long gone.

    • nezi 7 hours ago ago

      This paper isn’t saying that it doesn’t matter what program you do, it’s saying that other variables, not directly related to the method of weight training, matter more. It also assumes that you can extrapolate data from one individual training each limb with a different program to if that individual performs either program on both limbs. Maybe there are carryover affects to the lower load limb that you get from training heavier with the higher load limb that you wouldn’t from training both at a lower intensity.

    • zahlman 6 hours ago ago

      From my recollection, this is a quite common issue with studies in this topic area.

    • olalonde 5 hours ago ago

      Also, it's more difficult to reach true failure with lower load, people tend to stop too early.

      • samiv a minute ago ago

        False,

        failing to lift is not the same as lifting until failure.

        Consider, if I load up the bench press to 200kg I won't get a single rep. If I try to rep it I'll fail but I'm not lifting until failure.

        If I load it up to smaller weight lets say 100kg and crank out rep after rep I'll get much closer to training to failure.

        It's like integration, the smaller the infinitesimal the closer to the true value you get when you sum up (integrate) all the parts.

    • ed 9 hours ago ago

      this wasn't a study of absolute growth (sure - newbie gains), but rather the difference between high and low load programming within individuals.

      • Nevermark 8 hours ago ago

        > the difference between high and low load programming within [newbies]

        Fixed that.

        As the comment you replied to noted, newbie gains are remarkably sensitive to any stimulation, and insensitive to the type of stimulation. Because going from zero to any resistance training is a massive stimulus increase, on a long-term under stimulated system.

        The study does confirm that. The data it produces is useful.

        What this study doesn't do, is help newbies (or anyone) choose the most effective practices to adopt. Because 10 weeks is way too short to identify best practices for any sustained program.

    • goodpoint 3 hours ago ago

      "HN dismisses study without understanding it"

    • RickyLahey 6 hours ago ago

      this is peak gym bro science

    • throwaway713 6 hours ago ago

      > Yeah this is why.

      Guys, the study has been refuted by AstroBen. No need to read it.

      • orleyhuxwell an hour ago ago

        Yeah, that's pretty much it. The counterarguments don't address what AstroBen noted.: newbies get high gains from any kind of stimulus. The paper has simply confirmed the common knowledge teached in universities.

        The problem is, after you are no longer a newbie you may train for years with very little progress, and that's when you need to start differenting stimulus, being strategic about it - otherwise you may stay stuck.

        And unfortunately the paper doesn't address or refute that, while it's coverage (or even the title of this hackernews) may suggest otherwise.

  • armcat 13 hours ago ago

    I thought it was already well understood/researched that it's not the weights that matter, but effectively taking your sets to muscular failure. While one might think "I can do 50 reps with low weights" there is practical aspects to this - you don't wand to spend hours at the gym, and doing heavy weights at 5-7 reps is sufficient as long as you are close or at muscular failure.

    • safety1st 9 hours ago ago

      There are a few issues with taking every set to failure, the most important being that it will substantially increase your risk of injury. It sounds great until you consider compounds like the deadlift that can ruin your back if your form is bad, and by definition, going to failure means your form will be imperfect at some point. There are lots of macho powerlifters out there with permanently ruined spines who will probably die earlier than they would have otherwise, due to mobility degradation.

      Particularly as you get older you become more injury prone and your recovery time slows down. This necessitates being cautious about how quickly you increase weight and how often you go to failure.

      The better goal to target is increasing volume, where volume is defined as Sets x Reps x Weight. The literature doesn't conclusively establish that any one of these is "more important" than the others for hypertrophy. The only real caveat when you follow this rule is that at a certain extreme of low weight / high reps (like 50 reps) you wouldn't actually be doing resistance training anymore, it'd be cardio.

      • samiv 41 minutes ago ago

        Your point about the injury risk going up is valid. That being said going to failure and beyond is extremely effective way to train.

        As I mentioned in another comment a possibile way to mitigate the risks is to reduce the load and make the exercise harder and increase the time under load by slowing down the exercise.

        Also it's a good idea to swap from a higher risk exercise to a safer one to crank out the last reps. For example from squat to leg press.

      • Retric 9 hours ago ago

        2 reps in reserve is fine and far less painful, but you need to go to actual failure often enough to know where failure is on each set. I’m nerdy enough to suggest rolling a 20 sided die for each set, and on a 1 take it to failure it’s not that complicated and keeps your predictions honest.

        As I understand it taking a set near failure works reasonably anywhere between 5 to 30 reps, but 30 well controlled reps with good form * 3+ sets for each muscle group gets really boring.

        • nrhrjrjrjtntbt 7 hours ago ago

          Boring is subjective though. For some like me the ideal weight gives endorphins where as too much feels like cortisol. Too light is sort of nothing. So I aim for that "yeah I pushed something" feeling. Which isn't failure.

          • Retric 6 hours ago ago

            Let’s be realistic, everyone goes through periods when they just don’t want to work out.

            So optimal in terms of personal preference is defiantly worth considering alongside optimal in terms of results, but optimal in terms of returns on effort defiantly has a place at some point in our lives.

            • nrhrjrjrjtntbt 3 hours ago ago

              Yes guess it depends on your goals. Whether you are doing it for health, vanity, work or competitions will adjust the calculus.

            • matwood 4 hours ago ago

              This is key to recognize. Even when you don’t “feel” it you still go and do your program. But, when you do feel good, you go and push.

      • acoard 7 hours ago ago

        What about longer rest periods? For example if I wait 1hr between sets I can do full weight again without dropping down weights with a 2-5min break. In fact I can get multiple more sets in and significantly increase my total volume if I spread a workout over a day (which is easier with WFH). Any thoughts on this? Is there not enough muscle fatigue with this approach?

        • travisjungroth 7 hours ago ago

          Hard to stay warmed up that way. What you’re describing is how people tend to get big without the gym (lifting heavy things through the day) but they also tend be pretty active in between (think farm work).

          But as long as you’re not going so hard you risk injury, it might be great overall. Could be really good for your mental state.

      • siddboots 8 hours ago ago

        I think the total volume idea is more flawed than you realise. Pretty much everyone would be able to achieve greater volume, on any exercise, just by decreasing the weight, so your high rep caveat is covering up for quite a lot. This is true mathematically for an Epley style model for example.

        • matwood 4 hours ago ago

          > Pretty much everyone would be able to achieve greater volume, on any exercise

          I’m not sure this is true and it might be the opposite. Lactic acid will build up with light weight while trying to hit a volume number that will make it hard for people to finish.

          • Leherenn 2 hours ago ago

            Anecdotally, my gym had a "challenge" some times back where the goal was to achieve the max total volume in one set without pause.

            I tried various combos of weight* reps, and in the end the optimum was somewhere in the middle because no matter how light the weight there was a limit for me at about ~150 reps.

            In my case, the curve would be: total volume increases quickly initially at you go from max weight/1 rep to something like 20/30 reps, then something of a plateau as things equalise, then it goes down again as you reach the max reps threshold.

            • matwood 2 hours ago ago

              Great point. Personally I find lactic acid build up way more limiting for me than muscle fatigue. It's why I gravitated towards power lifting.

    • kace91 13 hours ago ago

      >While one might think "I can do 50 reps with low weights"

      The caveat is that you need anaerobic training. Low enough weight and it’s cardio, you don’t get giant legs by walking to failure for example.

      • nnutter 10 hours ago ago

        Has anyone really ever walked to failure on a regular basis? I typically have to stop because of blisters not muscle failure. (The furthest I've done is 12 miles with +10% weight.)

        • exq 9 hours ago ago

          I backpack often (usually 8-13% bodyweight in my pack) and during long summer days I can comfortably push well into the 30 mile per day range if there isn't too much vert to slow my pace down. My feet get sore, brain gets tired, and I run out of daylight well before any sort of muscle failure in my legs. If you aren't used to walking from sunrise to sunset doing so would build muscle, but your time would be better spent on a progressive overload leg routine in a gym.

          • LorenPechtel 8 hours ago ago

            Yup, I have never gone that far (but my summer hiking is entirely at high elevation with lots of climb) but I have never found anything like a failure point--I wear out because of time (not even daylight--I've made navigation errors that left me out there well past sunset), not muscle failure.

        • worthless-trash 10 hours ago ago

          I used to persistent hunt to failure, ended up with bulky calves and tibialis.

          • bglazer 9 hours ago ago

            Where were you doing this? Were you ever successful? How did you do it, like what were your tactics? So many questions!

            I’ve never heard about modern people doing serious persistence hunting, except for a stunt that I read about years ago. I think it was organized by like Outside or some running publication that got pro marathoners to try and they failed because they didn’t know anything about hunting

            • conception 8 hours ago ago

              Right? Where’s the well written blog post on this I want?

        • UI_at_80x24 10 hours ago ago

          Check anybody that has done the AT.

          • LorenPechtel 8 hours ago ago

            You think they hike to failure??

            (And you should be looking at the CDT, anyway.)

      • vjk800 4 hours ago ago

        I don't know. All cyclists I know seem to have massive thighs. And these are amateurs who don't do any kind of strength training, just hours and hours of cycling every week.

        • samiv 36 minutes ago ago

          There's a difference between the guys who cycle Tour de France vs the ones who go around in the velodrome.

          The former group is endurance athletes with skinny legs and the latter group is more focused on maximum power. Similar to marathon runners vs sprinters.

          The pro velodrome cyclists do tremendous leg training programs specifically to develop the muscles. It's not the cycling that builds that muscle.

        • kace91 3 hours ago ago

          >All cyclists I know seem to have massive thighs.

          Yeah uphill cycling or sprints probably go anaerobic at times, you can tell because you need to stop from the muscle burning/refusing to move, rather than going out of breath or general tiredness.

      • solumunus 6 hours ago ago

        Well you’re not applying much mechanical tension to the quadriceps when “walking to failure”. This is nowhere near analogous.

    • xnx 13 hours ago ago

      Well understood, but not widely known. The myths and superstitions around anything health related are frustratingly durable.

    • toshinoriyagi 9 hours ago ago

      The weight does matter. You will never get bigger if you don't add weight to the bar, and you will never get bigger if you only train at 1% of your 1 rep max, no matter the number of reps. Producing a training stimulus requires placing the muscle under sufficient tension (enough weight) enough times to be at or near failure.

    • calmbonsai 6 hours ago ago

      There's also the risk of injury.

      At very low reps and high weight, particularly for highly coordinated motions (squats, dips, pull-ups, Pulver press back-extensions), there's a much higher chance for injury due to insufficient support at one or more positions within the entire range of concentric and eccentric efforts by all activated muscles. We all have, at the very least, minor intrinsic asymmetries that need explicit addressing.

      There's also intra-set recovery. Roughly (very roughly) speaking, your endo-neuro-muscular system "adapts best" where there is a refractory period for a reset-to-quiescence between exertions.

      There is real truth to "muscle memory" and the exclusive way to achieve that (and avoid injury) is through a sufficient amount of well-formed repetitions. The only way to achieve those repetitions is by using a resistance that's sufficiently low.

      • vjerancrnjak 5 hours ago ago

        Asymmetry is normal and you cannot address it (outside of repeatability of movement, aiming for no form degradation during high load).

        As long as your movement does not degrade horribly, asymmetry is fine.

        Even before strength training, your one arm is dominant, more precise. But this has an effect on your leg as well.

        Doing unilateral work will never change that asymmetry. As you get stronger, due to drastically different activations of the nervous system between the sides, you will get slightly different adaptations.

        Looking at powerlifters, most of them have visibly different sizes of hip, leg musculature between sides. They even have drastic flexibility differences where one hip goes deeper, or the musculature makes the barbell sit skewed on the back.

    • fudged71 11 hours ago ago

      Brad Schoenfeld Has been on this body of work for a long time, and he is "Mr. Hypertrophy" in the field. So yes

    • sedivy94 7 hours ago ago

      Novelty of stimulus is a huge factor, especially as training continues over years. Failure from a set of 20 is very different than failure from a set of 5, and bodybuilders will periodize their training to cycle through the different flavors of stimulus. I think a big contributor might be neuromuscular adaptation. Cycling through those different intensities over training periods measured in months will make this apparent anecdotally.

      • solumunus 6 hours ago ago

        > bodybuilders will periodize their training to cycle through the different flavors of stimulus

        Some will, many won’t. It’s clearly not necessary.

    • kombine 5 hours ago ago

      Training to failure for me personally only brought injury and set back my progress by weeks.

      • samiv an hour ago ago

        If you were a newbie just getting started.. the ligaments and tendons take much longer to strengthen than the muscle. So the muscles getting stronger will outpace the connective tissue.

        Second potential issue is too much training vrt recovery.

        A good way to add safety margin when training to failure is to reduce the weights and slow down the exercise and increase the time under load.

        For example bench press, do 5s down (eccentric), 5s pause (isometric) and then (optionally) 5s press (concentric). Your weights will go way down because this exercise will be so hard. But the stress on the joints and ligaments will be reduced.

    • landl0rd 9 hours ago ago

      Fifty is excessive but you’re better-served doing 12-20 reps more than fewer, heavier reps if you’re pushing hypertrophy and already well-trained.

      • cornel_io 3 hours ago ago

        This article claims that's false, that 8-12 at higher weight leads to the same result as 20+ at lower weights.

      • taneq 7 hours ago ago

        That matches what I've been told by various personal trainers. 6-8 reps if focusing on strength, ~12 for all round, and 16-18 for size/endurance. Do three sets, weight should be enough that the last couple of reps on the first set are a bit of a struggle. Subsequent sets just push through as far as you can.

        • hatefulheart 7 hours ago ago

          Your trainers clearly never read Starting Strength.

          • taneq 2 hours ago ago

            No idea, I certainly haven't. This was decades ago, though, so it's entirely possible that established best practice has changed.

    • elevaet 13 hours ago ago

      What about the old gym adage "training to failure is failing to train" - is there any physiological basis for this, or is it mental, or just a myth?

      • wswope 13 hours ago ago

        That’s a Pl/Oly mindset rather than a BB/hypertrophy mindset. Totally valid advice in the right context.

        Long story short, failed reps get much more risky and problematic as the weight you’re lifting approaches your 1RM.

        • Moto7451 9 hours ago ago

          Exactly this. When I was in my best shape my deadlift and squat were in/on the way to 2.5-3x my body weight. You don’t want to fail that without a lot of help and safeties.

          Note for the uninitiated: That figure is not even impressive or competitive with competition lifters. This is just “guy who put in the time and work” numbers.

      • NoLinkToMe 7 hours ago ago

        It holds true, but with some caveats.

        Generally training to failure is completely fine for say a set of tricep extensions. Generally safe.

        However, training to failure on compound lifts like a deadlift or benchpress, or involving sensitive muscles like a shoulder press, isn't.

        Technique generally suffers at the point of failure. Making a habit of doing thousands of repetitions in the next decade at the point where technique fails, on an exercise that can mess up your back permanently, or your shoulders, is bad advice.

        For these exercises it's better to stop 2 reps short of failure. This is more safe. Also it requires moderate recovery getting you back in the gym quicker, meaning you can compound more incremental improvements in a given training period (say 5 years).

        Even then, some still cautiously go to failure to keep an understanding of what their failure point really is. You could go for a PR once or twice a month for example and go to failure, with a proper warmup, spotter etc. But purely for hypertrophy there's not really a point, this is more for strength training.

        Generally people that say they train to failure mean 2 reps in reserve. Training to absolute failure on all muscles is very rare and generally advised against.

        • calmbonsai 6 hours ago ago

          True. Generally, the more isolated the exercise and the smaller the muscle the "safer" it is to train-to-failure at a higher duty-cycle.

          Put another way, you can do crunches to failure every single day, but you'll want to keep some reps in the tank for squats and you'll want to plan on at least 12-24 hours of recovery between squat sessions.

      • teecha 11 hours ago ago

        not an expert, 2 years of serious lifting, but this is probably a good adage for the average person from my current understanding

        training to failure puts you at higher risk of injury and there are diminishing returns as you approach your 1 rep max and/or failure

        hypertrophy can happen with more reps or more weight

        strength gains are usually just focused on progressive overload

        though, of course, hypertrophy will happen either way and contributes to increased strength, but this seems to be further confirmation that you can gain muscle size either way

      • nzeid 11 hours ago ago

        It's definitely way more nuanced than that. You have to approach exhaustion to get the body to eventually build strength. But you need to carefully time your rests/deloads and handle plateaus with more volume.

        • thatcat 10 hours ago ago

          Where could I find more information on proper set timing?

          • aeonik 37 minutes ago ago

            This guy has a PhD in exercise science and is a very evidence based dude and breaks things down very nicely.

            https://youtu.be/DupQfkoI-Sc?si=QK_w2d99TcvNcQsD

          • matwood 4 hours ago ago

            It ends up being personal, but you want enough time to catch your breath and be “ready” to go again, but no more.

          • Moto7451 10 hours ago ago

            Honestly from a personal training/lifting coach. When I could spend serious time in the gym there’s a lot to just having someone with expertise for 30 minutes to give perspective. You can do a lot of it over video today as well.

            In general YouTube is a good resource. There are a lot of respected coaches that also produce content.

      • kace91 13 hours ago ago

        I’ve never heard that, it’s usually the opposite- people do strip sets and the like to reach failure

      • coffeebeqn 6 hours ago ago

        Failure also taxes your nervous system and joints which don’t take as kindly to stimulus as muscles do and take longer to recover (or accumulate damage in case of joints)

    • amelius 13 hours ago ago

      How about making muscles fail by stretching them under load?

      • mrob 13 hours ago ago

        Depending on what you mean by "fail" and "stretching", that sounds a lot like eccentric training [0] (a.k.a. "negatives"). It's effective but notorious for causing delayed onset muscle soreness.

        I trained myself to do pull-ups using this method, repeatedly lowering myself in a controlled motion from the top position while I was too weak to actually pull myself up.

        [0] https://en.wikipedia.org/wiki/Eccentric_training

      • jimbo808 13 hours ago ago

        Sounds like a great way to injure yourself, also would only work for eccentric motion

        • amelius 13 hours ago ago

          To me it doesn't sound much different than "taking your sets to muscular failure".

          • jimbo808 12 hours ago ago

            Not all muscles resist extension, some do the opposite and contract.

            • pasquinelli 10 hours ago ago

              i don't understand what this means. the stretch feeling is an involuntary muscle contraction that is happening to resist extension on the opposite side.

    • vasco 12 hours ago ago

      > Loads for each set were adjusted to ensure that volitional fatigue was reached within 8–12 and 20–25 repetitions for the HL and LL limbs, respectively

      I would argue both categories of the study are about low reps. I don't see how the body would tell the difference between 12 and 25 reps. If you said between 5 and 500, like it has to meaningfully take much longer, otherwise why would doing something so similar have any meaningful difference?

      The way I think about it is that nature mostly reacts to order of magnitude changes. 12 to 25 is the same thing.

      Like why not make a study to see if its more nutritious to eat dinner in 15 or 20 minutes?

      • pjc50 12 hours ago ago

        This is spoken like you've never done any reps at all?

        • vasco 12 hours ago ago

          There's not much difference in hitting max at 12 and at 25, from anecdotal experience. The study corroborated that as well, even though with small n.

          • solumunus 6 hours ago ago

            What do you mean by there’s no difference? The difference is in the relative load needed in each example.

            • vasco 3 hours ago ago

              Well of course you change the load, but the stimulus is interpreted the same way by the body. I didn't think the question was at that level.

      • mnky9800n 12 hours ago ago

        I feel like I would definitely notice if I went from 12 to 25 reps on any exercise I do. Although typically I max out at 8 before adding more weight.

        • Dylan16807 10 hours ago ago

          > I feel like I would definitely notice if I went from 12 to 25 reps on any exercise I do.

          To be clear, the implication is that 12 and 25 have different weights so they tire you the same amount. Do you think it would be a very strongly felt difference in that situation? What would the difference feel like?

          • mnky9800n 2 hours ago ago

            Yes, this is why classic body builders like high reps because they get the pump but you can get the same growth (and there’s lots of research saying more) with training to failure with low reps and high weight but it doesn’t give you the pump.

        • vasco 3 hours ago ago

          You consciously notice of course, like what kind of argument is that. The point is the stimulus is the same for the body unless you change it by orders of magnitude, the study agrees that this is the same also.

  • DiskoHexyl 4 hours ago ago

    Age: 22+-3 AND with that weight to ffbm ratio not only untrained, but at least slightly (I’m being generous here) overweight.

    With these pre-requisites it almost doesn’t matter what kind of physical activity one does- the muscles will grow anyway. It’s when you are older and/or accustomed to some kind of physical training, that you really noticeably benefit from resistance training.

    And still, that ‘almost’ part does a lot of the heavy lifting here. I don’t believe it’s really possible for a couch potato without any experience to correctly assess their 1RM. People with no experience with pain and effort typically can’t push themselves hard enough, so the entire exercise turns to a half-cardio anyway.

    And gauging 1 rep max in a bicep curl is especially difficult (saying nothing of a risk of injury).

    I understand the complexity and difficulty of researching the subject, but this entire article is no good and is hardly applicable to most of the population IMO

    • rocqua 2 hours ago ago

      Are you perhaps reading a personal advice in a paper, disliking the advice, and then finding that due to the experimental design, it doesn't work on you. And then, rather than concluding the paper didn't intend to inform your personal routine, instead conclude that the paper was badly designed? Or to put it differently. Have you considered how many people live in a way you would never consider close to acceptable?

      Because your points make sense but it feels like you are arguing against a bit of a strawman, or arguing for a mostly ideal situation rather than current reality?

      For overweight and understrength people, is it not very valuable to know that they don't need the extra steps of resistance training to see real improvement in strength and fitness?

      • DiskoHexyl 2 hours ago ago

        This doesn’t look like a particularly charitable interpretation of my comment, although my interpretation of the article isn’t either, so it’s only fair.

        And no, I am not looking for a personal fitness advice in scientific research anymore (too late for that), but am rather trying to see its applicability to others, as per my understanding of those others around me.

        Most people in the developed world aren’t 22-year old males. A significant part of the population is comprised of the elderly or middle-aged, a lot of those people have pre-existing injuries due to under- (too sedentary) and over-use (blue collar work, youth sports). Approaching physical fitness in those groups has its its own set of requirements and limitations, and I believe that in many cases resistance training is a more safe and efficient choice.

        Not saying that the youth and children are unimportant, but typically they are already well covered by the organized sports and pt classes in schools and universities, unlike the adults.

        My opinion is that the study is both badly designed (likely in a way to make it easier to implement) and is not applicable to the majority of the population.

    • vidarh 3 hours ago ago

      > I understand the complexity and difficulty of researching the subject, but this entire article is no good and is hardly applicable to most of the population IMO

      Most of the population is untrained, and in many countries a majority is overweight.

      I don't think your concern about "correctly assessing their 1RM" matters either - if anything that means the loads are even lower relative to actual 1RM, and their subjects were still getting results.

      It may not tell us much about outcomes at the top end, but more knowledge of what advice to give "most people" is important, and if they can get good results at low percentages of 1RM, it seems a lot more likely you'll get people to try.

      • DiskoHexyl 2 hours ago ago

        That is exactly the issue with incorrectly gauging 1rm- if it’s too low, than the supposed ‘resistance’ training with 70-80% of 1rm isn’t actually that.

        Is it fair to compare A to B, when the A in question isn’t exactly an A, but rather something closer to B?

    • vjerancrnjak 3 hours ago ago

      They have to start video recording the workouts. Even veterans in this academic field sometimes design workouts that just can’t be done to failure if you’re actually going to failure over 6-12 weeks.

      Even 1 workout sometimes has so many sets prescribed where I cant imagine all of them were actual failure

    • sigmoid10 3 hours ago ago

      >It’s when you are older and/or accustomed to some kind of physical training, that you really noticeably benefit from resistance training.

      Do you have any sources for that? I'm asking because that is a bold statement given the (almost non-) existing literature on pro athlete hypertophy. Especially since athletes in almost every sport don't even care about hypertrophy - unless you talk about pro bodybuilding. And there you have tons of pharmacological interventions, so it's not really easy to paint a picture either. I don't know a single good study performed on a significant set of tested natural bodybuilders regarding hypertrophy.

      Studies like this are also aimed at couch potatoes, because that is the normal population, so the results will be applicable to most people, which in turn is important when you want to get funding for your research. In that sense it also doesn't matter that these people will not have reached their full neuromuscular connection compared to actual weightlifters, because most people haven't either. So the results are still relevant. Usually when scientists sell this kind of research to grant departments, they try to provide a benefit to geriatric or otherwise medically impaired people, so that existing treatments may be improved. Studying muscle building itself just for the sake of it in gymbros is not a good strategy unless you want to spend your own money. And this stuff quickly gets very expensive if you want to do it right.

  • weinzierl 13 hours ago ago

    If I read this correctly the gist is that it does not matter if you use heavy weights with few reps (common body builder wisdom) or lighter weights with more reps. As long as you always exercise to complete muscle fatigue you'll get the maximum for your genetics (which itself varies a lot).

    • bob1029 11 hours ago ago

      There's no way this works in practice. A lot of heavy lifting (maximums) is about neurology and mind-body training. You cannot develop the ability to deadlift 405lbs by spending 2 hours using a cable crossover machine every day. Picking up something that weighs 2x more than you do requires your brain to send an extremely strong, synchronized signal. This is something that takes a lot of practice to develop. You have to consistently push your maximum voluntary effort in order to expand this capacity.

      • motoboi 3 minutes ago ago

        This is very interesting and explain why construction workers can lift 200kg but when they migrate to body building they lost that ability less that a year later.

      • jjj123 11 hours ago ago

        Right, but this post is about hypertrophy (big muscles). Not about heavy lifts.

        • bob1029 11 hours ago ago

          Well one thing can lead into the other over time. If you can lift 405 once, 315 for reps becomes pedestrian and 225 becomes boring. Lifting that much weight will turn you into a monster faster than if you had not pushed for that capacity. I've seen people who can treat a 225lb barbell as if it's unloaded and 100% of them look like dragon ball Z characters.

          • paulmooreparks 10 hours ago ago

            Body mechanics, leverage, and neuro-muscular connection definitely come into play. I could deadlift 430lbs for reps at my peak, and I while I was no string bean, I also didn't look all that muscular compared to the other lifters at my gym. I have ridiculously long arms relative to my height and relatively shorter legs, which gives me an advantage for deadlift. I had monstrous-looking guys watch me lift and then ask me what stack I was on. They didn't believe me when I said I was natural.

      • toshinoriyagi 9 hours ago ago

        There is a minimum weight you must use to create a training stimulus, but yes, you can increase your 1RM with higher-rep sets (again, to a limit, they can't be sets of 100, the weight is too light).

        To increase your 1RM at the most optimal pace, yes you need to specifically train the movement so that you can benefit from improved technique and neurological adaptation. But if I do tricep, pec, and front delt isolation exercises at higher reps, to failure, and see significant hypertrophy in these muscles, my bench press will be stronger, other things constant.

    • rorytbyrne 12 hours ago ago

      > heavy weights with few reps (common body builder wisdom)

      It is strength training (not body builder) wisdom to use heavy weights with few reps. Hypertrophy (i.e. body builder) programmes usually call for 8-12 reps, which implies relatively low weights.

      • NooneAtAll3 12 hours ago ago

        is "8-12" not "few" for you?

        • rorytbyrne 11 hours ago ago

          Relatively speaking, no. Strength training (as opposed to hypertrophy) calls for fewer reps, around 5 per set.

          Many people advise spending about a year doing more sets of fewer (~5) reps to build strength, and then switch to fewer sets of more reps (8-12) when you want to build muscle mass.

          Point being, the idea of doing lighter weights until failure is already kind of there in body building wisdom.

        • SoftTalker 11 hours ago ago

          3-5 reps per set for powerlifting training. Competition lifts are a single rep.

        • solumunus 6 hours ago ago

          No that’s definitely considered to be a moderate rep range. Roughly speaking low is 1-5, mid is 6-12, high is 12+. Above 20 is practically irrelevant.

        • throwaway6734 11 hours ago ago

          1-3 is few

    • toomuchtodo 13 hours ago ago

      Can we replicate the process of reaching muscle fatigue/failure to spur muscle growth without the strength training or anabolic steroids? Think GLP-1RAs but for this specific biological pathway.

      https://www.biopharmadive.com/news/lilly-terminate-obesity-t...

      https://www.sciencedirect.com/topics/medicine-and-dentistry/...

      • toshinoriyagi 9 hours ago ago

        Steroid use has been shown to increase muscle in untrained males by around 25-30% I believe, without adding any exercise. That doesn't accomplish too much. If you want any worthwhile results, you will still have to train, although the steroids produce significantly more results for the same investment.

        • QuercusMax 5 hours ago ago

          Andre the Giant said he never worked out, he just wrestled. He had some kind of growth hormone disorder, if I recall.

          Think about gorillas, who are pretty similar to us - they don't lift weights in the gym, do they?

          • samiv 30 minutes ago ago

            Andre the Giant was also not particularly athletic or healthy. He was just a huge guy caused by disruption in the growth hormone at some point in his life and he died of alcoholism.

          • tormeh 4 hours ago ago

            Yeah, muscles are mostly about genetics, just like anything else. A mouse won't become a rhino by lifting. Humans are so incredibly genetically homogeneous that it can sometimes be tempting to ignore this, but even between humans the variability is quite large.

      • allan_s 12 hours ago ago

        My understanding is that anabolic steroid are somehow close to what you're thinking about? It's just that as anything taking a simple shortcut , it comes with unwanted effects

      • stuffn 10 hours ago ago

        The reason no one has found a better way is because hypertrophy is because it’s well understood and there’s no “better” solution. mTOR is the primary hormone pathway.thy increase the adaptation ceiling by increasing RBC, reducing protein breakdown, etc. Thereby reducing rest needed, so mTOR is heavily unregulated.

        This is one of the view places where “if we could we would” is the correct answer. There is so much money in the space of anabolic cheating, the clandestine scientists would’ve already developed it.

    • zemvpferreira 13 hours ago ago

      It’s worth noting that muscle is not all the same. If you’re just into bodybuilding then sure, proximity to failure is what matters. For athletics though, there still seems to be a big impact in the rep range you work in.

      • d-us-vb 12 hours ago ago

        This. Muscles can be optimized for volume/endurance or power, or some balance between them. Taking legs as an example: Powerlifters obviously go for pure power, whereas runners need a bit of power but mostly endurance, whereas cyclists need more power than runners but more endurance than powerlifters.

        All of these benefit from weight training, but depending on the sport, the programming will be very different.

        • zemvpferreira 37 minutes ago ago

          Since I'm nitpicking let me point out that powerlifters train for strength. Power is an altogether different (though related to a degree) muscular/neurological characteristic. Power would be more closely related to olympic weightlifters or sprinters/shot-putters etc. Endurance could also be broken into alactic/lactic/aerobic capacity which makes a huge difference at the margins where athletic excellence is made. Nits aside your description is 90% there.

        • allan_s 12 hours ago ago

          I think I know where they're coming from as I used to have a similar wrong model. I thought strength = more muscle cells and endurance = just better heart/lungs to deliver oxygen and clear waste like CO2 and lactic acid.

          Turns out muscle fibers mostly grow bigger rather than more numerous, and there are different fiber types (slow-twitch vs fast-twitch) that adapt based on how you train. So for the same muscle, an Ironman runner and a guy doing heavy low-rep squats will develop different fiber characteristics: you can't fully max out both.

          I'm simplifying, but learning this changed a lot about how I understand exercise at the biological level.

    • kace91 13 hours ago ago

      It is actually common bodybuilder wisdom to go for the lighter version.

      Stereotyping, weightlifters who go for max numbers do 1 set of a million pounds and rest three hours between exercises, while bodybuilders do thirty exercises a day for 8 series of 15 reps each.

    • MattRix 12 hours ago ago

      Unless I’m missing something, this has already been known, though the hypertrophic benefits start to reduce beyond 30 reps.

  • ismailmaj an hour ago ago

    Even if true, high rep is impractical, otherwise we'd see people doing body weight exercises only reach high levels of bodybuilding.

    Even around 1900, it didn't matter if you were a genetic freak, you needed a barbell to win competitions.

  • wallaBBB an hour ago ago

    You cannot be strong without being big and you cannot be big without being strong.

    Of course there are levels to this, variations within “weight classes”… but in general this holds true.

    Also consistency trumps any program.

    • samiv an hour ago ago

      False.

      Strength as measured by mostly powerlifting is impacted by a huge factor by the body mechanics, i.e the length of the various body parts, secondarily by tendon attachments and then finally by variations in tissues

      • wallaBBB 38 minutes ago ago

        Thats the variation within the classes. And there will always be outliers, but even if you look at bodybuilders in 100+ kg, they are not what you’d call weak even if they don’t optimize for strength.

        • samiv 32 minutes ago ago

          Relative to their size a lot of them are weak.

          Again despite size it's the body mechanics that determine most the physical lifting capability of any individual in any particular lift.

  • samiv 2 hours ago ago

    As a natty bodybuilder for over 30 years for anyone aspiring towards fitness and starting at the gym my most important advice is

    "Put the phone away and bust some ass"

    I see way too many people (the great majority) completely sabotage their training by putting the weights down when it starts to get hard and get on their phone.

    When the weights get hard is when the real set begins. If you don't do the hard reps you deny yourself the stimulus required for adapting to overcome the stress, I.e the growth.

    • MarcelOlsz an hour ago ago

      This is why having a buddy/spotter is so important. On every lift my friend spotted me an extra 3-4 reps that I would not be able to do if I went just myself and kept going until the last rep was 95% him and 5% me. First guy to automate spotting is an instant billionaire.

      • samiv an hour ago ago

        Depending on the exercise you can also do this without a spotter.

        Either do cheat reps and focus on the negative (works with small exercise such as bicep curls) or drop set or super set.

        My personal fav is the cheat and negative and I do it a lot for example in cable pulldown. Use a bit of bodyweight to pull it down and then 5s negative.

  • padjo 4 hours ago ago

    The quality of evidence in exercise training is generally pretty terrible. 10 week study with untrained college students tells you very little about what happens over a lifetime of lifting. Personally I’ve found that switching rep range on an exercise is a great way to break through plateaus.

    Ultimately you’re engaged in an n=1 study and general advice is of limited use. You need to learn what tools are available, how your body reacts to different stimuli, what keeps you consistent etc. Everything is context dependent, trying to find some universally “best” way is a wild goose chase.

  • n2y 2 hours ago ago

    The study assigned different training regimes to different limbs of the same person. If you think their measured effects do not reflect your own experience, I'd be interested in your fitness status and your result when you do the same. Otherwise it sounds a little like you are disputing the study because it showed something different to your belief.

  • leonflexo 6 hours ago ago

    I thought hypertrophic focused routines were their own subset. Starting with a high rep, like 20, decreasing something like 2/week while increasing the weight. You technically can increase load, but in my experience it isn't strictly necessary. 10-12 weeks down to 1-2 reps then 3-4 off to reset. This isn't a strength routine, simply for size relative to lift.

  • Imanari 12 hours ago ago

    For beginner lifters that might be true initially, but eventually weight will matter.

  • chistev 6 hours ago ago

    Firas Zahabi on focusing on consistency over intensity in training.

    https://youtu.be/_fbCcWyYthQ?si=gf39MLiqid9e6Szu

  • Analemma_ 13 hours ago ago

    I know it's practically de rigeur to jump into the comments and immediately complain about methodology for any study that makes it to the front page, and I want to emphasize I don't distrust their findings, but I would like to see an equivalent study go out longer than 10 weeks. When I've been taking weightlifting seriously I feel like I don't even start to notice hypertrophy until 8-10 weeks. I feel like 6 months is the actual period where results would matter, to me, but I assume "subject compliance" is pretty difficult to get for such a timeframe, if you're really watching dietary intake and ensuring subjects go to failure (which, to its credit, this study did).

    • mf_tomb 12 hours ago ago

      This is par for the course with exercise science. It's mostly fake. No blinding, small sample sizes, researchers with agenda, low duration, low funding etc. The good news is that doing almost anything works.

      • throwaway173738 8 hours ago ago

        Doing almost anything works better than doing nothing.

  • westurner 7 hours ago ago

    What about Time Under Tension?

    "Equalization of Training Protocols by Time Under Tension Determines the Magnitude of Changes in Strength and Muscular Hypertrophy" (2022) https://journals.lww.com/nsca-jscr/fulltext/2022/07000/equal... :

    > Abstract: [...] In conclusion, training protocols with the same TUT promote similar strength gains and muscle hypertrophy. Moreover, considering that the protocols used different numbers of repetitions, the results indicate that training volumes cannot be considered separately from TUT when evaluating neuromuscular adaptations.

    • coffeebeqn 6 hours ago ago

      So could I just do one super slow (some minutes) squat per week at like 60% and get all the benefits still?

      • user_7832 3 hours ago ago

        I’m not at all a biology expert, but if the squat is actually pushing you somewhat close to your limit (it’s not super easy), you’ll definitely get stronger. Case in point: isometric exercises. Also: folks who do planks for a few weeks/months.

  • bethekidyouwant 13 hours ago ago

    The group that did lower reps with higher weight, had the better one rep max at the end of the study, but they didn’t measure if the higher rep group had greater endurance. Which seems a bit odd, considering their conclusion is both groups grew the same amount of muscle which fine but if the muscle is adapted for something different in each group, you would want to capture that.

    • wiether 5 hours ago ago

      > both groups grew the same amount of muscle which fine but

      The focus was on hypertrophy, so 1RM or endurance doesn't matter in their case

  • metalman 2 hours ago ago

    I am afraid of trying to lift to failure. never once been in a gym, or trained for anything except marksmanship, but have alwayse been physical, with a lot of what I call "dirty lifts" in the course of getting things done,pushing 60 now. I do notice that after a stretch of realy hard work, and taking a day or two to rest and EAT, I will bulk, but nothing is by the numbers, except the day I took over the old blacksmith shop and we took the gentlmans anvil down, and lifted mine up, each of us grabing one end with one hand, my anvil weighs 460lbs, he was in his 80's and I was in my late 20's. I muscle everything around, steel, wood, round bales,but follow the philosophy of "just because you can, dosn't mean you should" which I believe is especialy true for realy big guys, because while you can build huge muscle, your cartlige and coligen is no better than an size small office guy with that florecent tan, where I have seen in the same frame, a big guy pushing 40, not moving good anymore, and foccused dweeb gettin his lunch zipps right through, doesn't even see the hulk. my point, if I have one, is that nothing counts, unless you can style it

  • mmmilanooo 13 hours ago ago

    It does matter. It's the only objective way to measure progress. A study doesn't negate that.

    • yjftsjthsd-h 12 hours ago ago

      I don't think so? If last week I could do 50 reps @ 5 lbs, and this week I can do 50 at 6 lbs (or 60 at 5lbs), then that's measurable objective progress

    • justatdotin 12 hours ago ago

      isnt the 1RM the measure of progress?

      • SoftTalker 11 hours ago ago

        If that's what you're training for, sure. If you just want to be strong, you can achieve that and avoid the highest injury risk by sticking with 5 reps or so.

  • henning 8 hours ago ago

    Yep, lots of different ways to get jacked. That means if you couldn't care less about strength, you can do pretty much any decent exercise that targets the muscle(s) you want to grow in a very wide rep range. Most people want a combination of both size and strength, so you can just do some sets of 5-10 if you aren't already. If you want to have a strong deadlift or squat or whatever, you should train that movement. Not as complicated as fitness social media people want to make it seem: train for what you want.

    • esperent 6 hours ago ago

      I don't think this is true. I've been following a fairly standard progression on several of the standard exercises over the last year and half. I've seen steady progression on leg press, which is a strongly stabilized and isolated exercise. I saw the same rate of initial progression on squats but then it dropped off and I haven't really seen any progression for six months.

      The issue is stability. I have to provide the stability for squats. The machine gives me stability for leg press. I won't get the stability I need for further progression, at least not at an optimal rate, just from squatting. I need to do complementary exercises.

  • Sporktacular 12 hours ago ago

    So resistance is futile?

  • cubefox 13 hours ago ago

    > Twenty healthy young male participants completed thrice-weekly resistance exercise sessions for 10 weeks.

    Not sure how much can be concluded from this.

    • cubefox 9 hours ago ago

      I think the downvoters need to read up on underpowered statistics.

  • hazard 13 hours ago ago

    tldr appears to be that if you work to fatigue it doesn't matter if you fatigue out with high weights vs low weights

    • vlod 13 hours ago ago

      I agree with this, but for those newbies be careful at what you define as "failure".

      I've f.up my MCL by not listening to my body and I have the stability of a typical 85 year old while I try and 'heal'. It takes longer as you get older (you're probably not 20 year old) and stupid stuff can really take you out.

    • andoando 10 hours ago ago

      There is certainly a difference in a slow twitch vs fast twitch muscle adaptation though

      https://pmc.ncbi.nlm.nih.gov/articles/PMC8139349/

    • chrishare 13 hours ago ago

      When training for muscle size atleast, but not strength. Presumably there are increased injury risks overall when lifting heavy (based on a brief search).

    • teecha 12 hours ago ago

      fairly new to lifting myself (2+ years taking it seriously) but this thing seems to jive with what I've read across different areas

      bodybuilders can build muscle size with high reps and lower weight or lower reps and high weight as long as they do it close to failure with only a few reps in reserve (rir)

      powerlifters, or those focusing on strength, usually go for high weight and lower reps because they might be training for a competition that focuses on 1 rep max and/or the body can really only handle so many reps when pushing it at 80-90% of 1 rep max

      neither is inherently better but a matter of what goals you have in mind, plus, hypertrophy contributes to overall strength, too

  • Torkel 13 hours ago ago

    I.e.

    No pain, no gain.

    • slashtmpslashme 10 hours ago ago
      • mahdi7d1 9 hours ago ago

        If it's not painfull you are not exerting enough effort at least that's the case in the gym. People who are refreshed and more energetic after going to the gym are the same people who won't improve beyond intermediate levels. The ones who let go of the any set at the first feelings of unease and never take a set close to failure.

        It's actually fascinating how an ancient proverb could line up with modern science so perfectly.

        • toshinoriyagi 9 hours ago ago

          It certainly does not need to be painful. I think most people will make a distinction between the burn of acidosis, or what you call unease, and actual pain indicating damage is occurring.

          But yes, if you never train close to failure you will not grow, not past beginner gains, unless you take steroids.

    • cyberax 12 hours ago ago

      This is really terrible advice that just discourages people.

      You absolutely can get significant improvements without (much) pain. DOMS during the initial stages is going to be the most uncomfortable part. Once you're past it, you don't need to push yourself to a breaking point, just to the point of mild exhaustion.

      This will provide you enough resistance to gain muscle mass and improve the bone density to healthy levels.

      • strken 12 hours ago ago

        Yeah, "no pain no gain" is probably the worst advice I've ever received. It encourages sedentary people to go hard for a week and then quit, which is the exact opposite of what works: starting with consistent easy sessions and adding progressive overload.

        Dynomight has a good blog post about this[0], but applied to running rather than resistance training.

        [0] https://dynomight.net/2021/01/25/how-to-run-without-all-the-...

  • amelius 13 hours ago ago

    Wait, why are we figuring this out only now?

    • overhead4075 12 hours ago ago

      A paper doesn't necessarily mean the information is new, but that there is now some/more evidence to support it.

      • amelius 11 hours ago ago

        True, but this kind of information is so basic it almost fits in the "world is round" category.

  • landl0rd 9 hours ago ago

    You can do the goofiest workout you can possibly imagine as a young untrained male and put on muscle. You will do so at roughly max rate regardless of what you do as long as it’s vaguely productive. This isn’t useful research ngl.