10 comments

  • nextos 15 hours ago ago

    Look into companies doing trials with a credible track record. For example, Immunocore has good T cell receptor designs to bind common antigens in breast cancer tumors. For solid tumors, including breast cancer, the protein ID is IMC-F106C. For advanced cases, this is usually combined with a checkpoint inhibitor.

  • pella 2 days ago ago

    Not a doctor, but gut microbiome modulation (e.g. fecal microbiota transplantation) is one of the most talked-about adjuncts for (metastatic breast) cancer right now.

    https://scholar.google.com/scholar?as_ylo=2022&q=fecal+micro...

    --- example:

    "Understanding the relationship between breast cancer, immune checkpoint inhibitors, and gut microbiota: a narrative review"

    https://pmc.ncbi.nlm.nih.gov/articles/PMC11557166/ ( Transl Breast Cancer Res. 2024 Oct 21)

      """
      Conclusions
      The composition of gut microbiota could help predict 
      the chance of response to immunotherapy, 
      and modulating gut microbiota has the potential 
      to enhance the  efficacy of chemo-immunotherapy 
      in breast cancer. 
      However, the available data relating to breast cancer 
      are limited. 
      Larger prospective studies are required 
      to further elucidate their role 
      as a biomarker and treatment.
      """
  • yread 2 days ago ago

    Depends on a lot of things. Subtype, ER, PR, HER2? For triple negative breast cancers some patients may avoid chemo if they have highly active immune system (TILs)

  • g42gregory 2 days ago ago

    Here is a possibly different (or supplemental) point of view, with repurposed drugs and metabolic interventions. I believed it would be applicable to the breast cancers: https://imahealth.org/research/cancer-care/

    • hazrmard 2 days ago ago

      Thank you very much! I had been reading up on effect of diet for treatment & management. I like the focus on citations.

  • incomingpain 2 days ago ago

    Step 1: See Oncologist and take their advice.

    Step 2: Definitely don't take internet advice. Disregard the following.

    Step 3: Hit the gym

    Step 4: Intermittent fasting + 50% fat, 50% protein diet.

    Step 5: Ask doctor for a standard run of Fenbendazole or Mebendazole

    Step 6: Play with them as much as possible.

    • anonzzzies 2 days ago ago

      > Step 2: Definitely don't take internet advice.

      then

      > Step 4: Intermittent fasting + 50% fat, 50% protein diet.

      > Step 5: Ask doctor for a standard run of Fenbendazole or Mebendazole

      Right...

      So definitely don't listen to this then.

      • incomingpain 2 days ago ago

        That's literally the joke... Good job.

        • anonzzzies 2 days ago ago

          Funny, considering there are boatloads of crackpots even on HN who actually believe this would work and advocate it all the time. I haven't heard from that dude who comments on everything with that he and his family only eat beef for a while so I assume they died of that great keto diet.

          • seattle_spring a day ago ago

            > I haven't heard from that dude who comments on everything with that he and his family only eat beef for a while

            Didn't know Jordan Peterson was on HN.